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e , Melanin production of 10 6 cells per strain retrieved from murine lungs and spotted on solid l-DOPA medium

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Right, volcano plot showing relative fold change (log 2 ) in ER-metabolite abundance versus log 10 (P value) from HEK293T cells expressing a sgRNA targeting intergenic region or sgRNA targeting SLC33A1

Workflow of GRX reduction of glutathionylated proteins Each method offers distinct strengthswhether for targeted validation or comprehensive redox proteome mappingand can be selected based on the study's scale, sensitivity needs, and sample type